Each capsule contains 250 mg of erythromycin (in the form of ethyl succinate) (D.C.I.); Exc .: colloidal silica, talc and magnesium stearate.
Components of the capsule: gelatin, titanium dioxide (E 171), indigo carmine (E 132).
Erythromycin is a macrolide antibiotic, which inhibits protein synthesis without affecting the synthesis of nucleic acids. Due to its stability in an acid medium, erythromycin salts are easily absorbed, both on an empty stomach and on a full stomach. After its absorption, Erythromycin diffuses to all organic liquids. In the absence of meningeal inflammation, the concentrations of Erythromycin in the cerebrospinal fluid are low, but in cases of meningitis, there is a passage of the drug through the blood-brain barrier. Erythromycin is concentrated in the liver (normal liver function) and excreted by the bile. After oral administration, less than 5% of the administered dose can be recovered in the urine in active form. Erythromycin crosses the placental barrier, although plasma levels in the fetus are low.